toss out some of yours then
There are too many variables that go into it for me to share mine with you.
We'd have to have the same party
The same gear
The same skills
The same stats
Just put all your sustained abilities on your second set of hot buttons for each character (if you have one that overwrites the other, just hotkey the better of the two). And before you're about to battle, toggle through everyone and make sure all of their sustained abilities are active. Don't waste your tactics on sustained abilities, just instant abilities.
Then go into tactics, make sure Wynn is healing your main tank when he hits 50% health and other party members at 75% health. And set your main tank to drink a pot at 25% health in the event he's taking big damage and you're waiting for Wynn's heal to refresh.
Then just set all the tactics for everyone else to assist your main tank using their best attack abilities. If you want an off tank, you can assign that tactic too.
I play a ranger but usually run into battle using Alistar, the first thing I do when I run in is blow my AE taunt so everything is on him, then I switch to my ranger and plug away with my arrows. I'm a master ranger so I have the l33t pets that do huge damage.
Setting up the tactics is just like setting up a raid in WoW or EQ, everyone has their own job. It's actually easier than WoW or EQ because you have total control and your party will do EXACTLY what you tell them to do. So you're removing the element of the moron behind the keyboard who didn't listen and kills everyone.